EFFECT OF INTAKE OF HIGH DOSES OF CAFFEINE ON ALVEOLAR BONE DENSITY IN RATS. A HISTOMETRIC STUDY

Authors

  • Joyce Pinho Bezerra Universidade Guarulhos
  • Marta Ferreira Bastos Universidade Guarulhos
  • Luis Ricardo Ferreira da Silva Universidade Guarulhos
  • Poliana Mendes Duarte UnG

Keywords:

osso alveolar, cafeína, histometia

Abstract

The aim this study was to evaluate, by histometric analysis, the effect of high doses of caffeine on alveolar bone density in rats. Twenty-four Wistar rats were assigned to one of the following groups: Test (n=12): 10mg/100g body weight/day of caffeine via drinking water for 56 days. Control (n=12): animals without caffeine ingestion. Fifty-six days after the initial of caffeine ingestion, the animals were sacrificed and the specimens processed in order to obtain decalcified sections. The bone density in the furcation region of the first molars was histometrically determined. Bone density was lower for caffeine group (81 ± 5.8%) when compared to non-caffeine group (83.4 ± 6.7%) (p<0.05). In conclusion, the present study demonstrated that daily intake of high doses of caffeine may have a negative influence on alveolar bone density.

Author Biographies

Joyce Pinho Bezerra, Universidade Guarulhos

Mestre em Odontologia, Universidade Guarulhos Aluna de doutorado em Odontologia, Universidade Guarulhos

Marta Ferreira Bastos, Universidade Guarulhos

Professora Assistente do Curso de Pós-Graduação da UnG, Mestre e Doutora em Ciências Biológicas

Luis Ricardo Ferreira da Silva, Universidade Guarulhos

Cirugião-dentista, Universidade Guarulhos

Poliana Mendes Duarte, UnG

Professora Adjunta do Curso de Pós-Graduação da UnG, Mestre e Doutora em Clínica Odontológica - Área de Concentração em Periodontia

Published

2009-08-16

How to Cite

Bezerra, J. P., Bastos, M. F., da Silva, L. R. F., & Duarte, P. M. (2009). EFFECT OF INTAKE OF HIGH DOSES OF CAFFEINE ON ALVEOLAR BONE DENSITY IN RATS. A HISTOMETRIC STUDY. Revista Saúde - UNG-Ser, 3(3), 05–09. Retrieved from https://revistas.ung.br/index.php/saude/article/view/424

Issue

Section

ARTIGO ORIGINAL